JACKSONVILLE, Fla. — The City of Jacksonville has approved a key construction permit for Mayo Clinic in Florida, paving the way for a $19 million build-out at its South Jacksonville campus. The project marks another step in Mayo’s multiyear, billion-dollar expansion to meet the region’s growing demand for complex medical care.
The permit, issued August 27, allows for the interior development of two floors — 40,064 square feet — in Phase 3B of the Patient Tower expansion. Work will include space for radiology, pharmacy, and other clinical support functions.
The Robins & Morton Group of Orlando is the contractor, with design work led by Perkins&Will of Atlanta and civil engineering by Prosser Inc. of Jacksonville.
Mayo Clinic’s Jacksonville campus, first opened in 1986, has undergone multiple expansions over the decades. Since 2016, Mayo has invested more than $1 billion in new facilities for patient care, biomedical research, and education, more than doubling its campus space by 2026.
“This will include clinical support functions for various departments of the hospital. The design is still underway for the use of the space,” Mayo Clinic Communications Manager Kevin Punsky previously explained.
This latest project follows earlier permits that covered a three-floor addition, new emergency department entrance space, and shell construction to allow for vertical expansion. The hospital tower, which originally opened in 2008 with 212 beds across six floors, has steadily grown to accommodate demand, now rising to 13 floors with 419 beds.
Mayo has also indicated the tower could eventually expand to 16 floors, allowing even more inpatient capacity in the future.
The expansion comes as Mayo continues to position itself as a global destination for patients requiring highly specialized care.
“The expansion of our hospital will enable Mayo Clinic to offer outstanding, high-quality care to more patients with serious and complex illnesses,” said Dr. Kent Thielen, CEO of Mayo Clinic in Florida, in a recent news release.
The $432 million campus-wide expansion plan announced in 2022 will add 121 new inpatient beds, including 56 intensive care unit beds, and further enhance Mayo’s role as one of Florida’s leading health systems.
Mayo Clinic’s ambitions extend beyond its patient tower. The health system is also expanding geographically, adding a 210-acre North Campus adjacent to its existing 392-acre medical center property. With this acquisition, Mayo’s Jacksonville footprint now totals nearly 600 acres, offering decades of future growth potential.
The first phase of the North Campus project, now underway, includes roadway construction and site clearing. Long-term plans call for up to 7.5 million square feet of facilities by 2045, encompassing outpatient services, clinical labs, housing, education, and even hotel space to support visiting families.
The Davis family, founders of Winn-Dixie, originally donated land for Mayo’s Jacksonville campus, and in 2022 conveyed the additional 210 acres to enable this next wave of expansion.
From its beginnings in 1986 as Mayo’s first campus outside of Minnesota, the Jacksonville site has grown into a regional anchor for health care, research, and innovation. With this latest $19 million permit and ongoing $432 million expansion, Mayo is setting the stage for the next generation of advanced medical care in Florida and beyond.
Originally reported by Karen Brune Mathis in JDR.
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