Several major companies are ramping up manufacturing investments across the United States, announcing new facilities, production expansions and job creation as firms strengthen domestic supply chains and meet rising demand in sectors such as pharmaceuticals, steel and advanced electronics.
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Industry leaders including Novartis, US Forged Rings, Akston Biosciences and Faith Technologies have recently revealed projects spanning multiple states, highlighting continued momentum in U.S. manufacturing development.
These investments come as companies seek to expand production capacity, shorten supply chains and support growing demand for high-tech products and industrial materials.
Pharmaceutical giant Novartis is planning to build a 46,000-square-foot radioligand therapy manufacturing facility in Denton, Texas, as part of its wider effort to expand research and manufacturing operations in the United States.
The new plant will focus on producing targeted treatments for patients with advanced cancers and will become the company’s fifth U.S. site dedicated to radioligand therapy manufacturing.
Construction on the project is expected to begin in 2026, with commercial production anticipated to start by 2028.
The Denton facility represents part of Novartis’ broader $23 billion commitment to expand its U.S. manufacturing and research footprint, which the company announced last year.
Over the past 10 months, the pharmaceutical company has already broken ground on four additional facilities across the country, demonstrating continued progress toward that long-term investment strategy.
The Texas project is expected to create jobs in several specialized fields including:
Local officials say the project could generate new opportunities for the regional biotechnology workforce while supporting broader economic growth.
The investment in Denton is estimated at $280 million and may qualify for nearly $9 million in state and local tax incentives, according to local reports.
Startup steel manufacturer US Forged Rings has selected Hertford County, North Carolina, as the location for a large-scale industrial production facility focused on steel forgings and industrial components.
The project is part of a three-phase development plan valued at approximately $875 million.
The first two phases alone are expected to create 625 new jobs in the region while supporting growth in domestic steel production.
“This investment represents an important step in our mission to strengthen American manufacturing capability in critical steel products,” US Forged Rings President and CEO Giacomo Sozzi said in a statement.
Founded in 2022, the company is part of the Sozzi family’s industrial group, which has more than four decades of experience in steel forging operations.
Once operational, the facility will produce specialty tubular products and forged components used in sectors such as power generation and heavy industry.
The plant will also manufacture industrial parts including:
The site will be located next to a steel plant operated by Nucor, a key supply chain partner for the project. Rail services will be provided by CSX Transportation to support long-distance freight shipments.
Production for the first phases is expected to begin in 2028.
Several other companies are also expanding their manufacturing presence with new facilities and production investments.
Animal health biotech company Akston Biosciences has opened a 31,000-square-foot manufacturing plant in Shreveport, Louisiana, marking a key milestone in its expansion strategy.
The facility is part of a $7 million investment aimed at increasing production of protein therapeutics designed for pet health treatments.
The site is expected to create 69 direct jobs over the next five years, with average annual salaries of around $100,000, according to local economic development officials.
Akston co-founder and CEO Todd Zion described the project as a significant step for the company’s growth.
“major milestone,” saying that it was critical to expand in the U.S. and aims to address unmet needs in pet health with its protein therapeutics.
The facility includes specialized infrastructure such as clean rooms for biologics production, quality control laboratories, cold storage systems and warehouse space.
Meanwhile, electrical equipment manufacturer Faith Technologies is planning to invest $79 million in a new production facility in Opelika, Alabama.
The project involves renovating a former distribution center previously used by Joann Fabrics.
Once completed, the site is expected to create around 200 jobs in the Auburn-Opelika metropolitan area.
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Faith Technologies manufactures electrical systems including switchboards, power modules and charging infrastructure used in energy, construction and technology markets.
The company’s modular electrical solutions are also designed for large data center developers and industrial customers, a rapidly growing segment of the construction and technology industries.
The wave of new investments reflects a broader trend toward reshoring manufacturing operations in the United States.
Companies are increasingly prioritizing domestic production to improve supply chain resilience, reduce shipping delays and respond more quickly to market demand.
At the same time, federal and state incentives, growing demand for advanced technologies and expanding infrastructure projects are encouraging firms to build new facilities across the country.
As industries such as pharmaceuticals, energy, electronics and advanced materials continue to grow, analysts expect manufacturing investment in the U.S. to remain strong in the coming years, with more companies announcing expansion plans and new production hubs.
Originally reported by Nathan Owens, Reporter in Manufacturing Dive.
